Research

Examples of Our Work

1) Determination of light-induced active state protein structures

Solution structures of the orange carotenoid protein (OCP) determined by small angle scattering under in-situ illumination depicted on the left side, illumination setup shown on the right side.

(Golub et al., J. Phys. Chem. B, 2019, https://doi.org/10.1021/acs.jpcb.9b05073; Golub et al., Photosynth. Res., 2026, https://doi.org/10.1007/s11120-026-01204-6)

2) Determination of solution structures of membrane proteins solubilized in detergent shell

Solution structure of the PSII complex reconstructed from SANS data using the DAMMIN routine (gray spheres) compared with the PSII crystal structure (PDB ID: 5kaf(16)) shown in cyan and violet.

(Golub et al., J. Phys. Chem. B, 2019, https://doi.org/10.1021/acs.jpcb.9b05073)

3) Time-resolved neutron scattering experiments show proteins at work

Setup for novel time-resolved quasielastic neutron scattering (TR-QENS) experiments with in-situ light excitation. This method enables us to directly examine the modulation of picosecond protein dynamics during the functional cycle of photoactive proteins in real time.

(Burankova et al., Biophys. J., 2026, https://doi.org/10.1016/j.bpj.2026.02.028)